Early Identification of Complement Dysfunction is Critical
Machaon Diagnostics provides industry-leading turnaround times for complement genetics, activation markers and related tests to support our clients managing these patients. Dysregulation of the complement system can quickly lead to catastrophic outcomes. Underlying root causes can be genetic, functional, autoimmune and other. Immediate recognition of factors causing clinical complications is essential for reducing patient morbidity/mortality (e.g., kidney damage while waiting for diagnosis/treatment decision) and wasteful spending (e.g., plasmapheresis when eculizumab is most appropriate).
Complement Testing with us:
- Industry-leading turnaround times
- Early detection of complement dysfunction
- Complement gene sequencing in 48 hours (STAT)
- sC5b-9 levels in 24 hours, 7 days a week
- Anti-CFH Autoantibody levels
Available through Clinical Trials Services. The CH50 is the most common assay to measure total complement activity in the classical complement pathway (C1 through C9) by adding patient serum to sheep RBC coated with anti-sheep antibodies. The minimum dilution that lysis 50% of the cells determines the CH50.