Home Test Search Results C3 Nephritic Factor
C3 Nephritic Factor

Justification

C3 Nephritic Factor is an autoantibody. It stabilizes C3 convertase. C3 Nephritic Factor is associated with approximately 80 percent of patients with DDD; it is also seen in approximately 40 percent of C3GN patients. It's not specific; however, detection of C3 Nephritic Factor supports the diagnosis of C3GN or DDD.

STAT: < 1 week

Ratio

Draw Tube: Red Top

Sample Type: Serum

Specimen Requirements

Sample Type Volume Required Minimum Volume Stability
PREFERRED Serum 1mL 0.5mL Frozen (-20C): 2 weeks
Frozen (-80C): 6 months
ALTERNATIVE - - - -
REJECTION CRITERIA Thawed in transit, refrozen or clotted sample
SPECIAL INSTRUCTIONS -

General Information

METHODOLOGY Ratio
STAT TAT < 1 week
STAT TAT Performance > 90% of results released in 1 week
ROUTINE TAT < 1 week
ALTERNATIVE NAMES C3Nef
DESCRIPTION This is not a direct measurement of antibody quality, but only a qualitative (indirect) measure of its activity in causing C3 conversion.
LIMITATIONS -
NORMAL RANGE -
ASSOCIATED TESTING -
REFERENCES

Ito N, Ohashi R, et al, C3 glomerulopathy and current dilemmas, Clin Exp Nephrol 2017(4): 541-551
Du Clos T, Mold C, Complement in host deficiencies and diseases, Clinical Immunology 2013: 252-269

SAMPLE REPORT Upon request
NEW YORK STATE APPROVED No

Test Codes

ORDER CODE P3366
CPT CODE 86161
LOINC CODE 23844-4