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LA Coag Antiphospholipid Antibody Panel

Justification

Custom panel for lupus screening and antiphospholipid antibody detection. Lupus anticoagulant and antiphospholipid antibodies increase the risk of arterial thrombosis, venous thrombosis, thrombocytopenia and recurrent miscarriage.

Panel Component Tests

aPTT Prothrombin Time (PT/INR) aPTT-LA (Lupus Sensitive) Russell Viper Venom Time (dilute) Anticardiolipin Antibody (IgG, IgM, IgA) Beta-2 Glycoprotein I Antibody (IgG, IgM, IgA) Antiphosphatidylserine Antibody (IgG, IgM)

STAT: < 48 hours (M-F)

Clot-based, CIA, ELISA

Draw Tube: Blue Top

Draw Tube: Red Top

Sample Type: Citrated Plasma and Serum

Specimen Requirements

Sample Type Volume Required Minimum Volume Stability
PREFERRED Citrated Plasma and Serum Three aliquots, 1mL each (Citrated Plasma);One aliquot, 1mL (Serum) Three aliquots, 0.5mL each (Citrated Plasma);One aliquot, 0.5mL (Serum) Room Temp.: 2 hours
Refrigerated: 2 hours
Frozen (-20C): 2 weeks
Frozen (-80C): 6 months
ALTERNATIVE - - - -
REJECTION CRITERIA Thawed in transit, refrozen or clotted sample
SPECIAL INSTRUCTIONS -

General Information

METHODOLOGY Clot-based, CIA, ELISA
STAT TAT < 48 hours (M-F)
STAT TAT Performance > 90% of results released in 48 hours
ROUTINE TAT < 1 week
ALTERNATIVE NAMES APS Panel, Lupus Anticoagulant, Antiphospholipid Antibody testing, Louisiana Coagulation APS Panel
DESCRIPTION -
LIMITATIONS -
NORMAL RANGE Interpretation: Normal
ASSOCIATED TESTING -
REFERENCES -
SAMPLE REPORT Upon request
NEW YORK STATE APPROVED -

Test Codes

ORDER CODE P1203
CPT CODE 86147x3, 86146x3, 86148x3, 85613, 85730
LOINC CODE 3181-5, 3182-3, 5076-5