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aPTT

Justification

The activated Partial Thromboplastin Time (aPTT) is a general coagulation screening test for congenital and acquired deficiencies of the intrinsic and common coagulation pathway factors (XII, XI, IX, VIII, X, V, II, and I). This aPTT uses a reagent sensitive to factor deficiencies, lupus anticoagulants, and heparin. Machaon Diagnostics offers three different aPTT tests (aPTT, aPTT-LA, and aPTT-FS), each with different clinical utility based on differences in sensitivity to the presence of factor deficiencies and lupus anticoagulants.

STAT: < 24 hours (7 days a week)

Clot-based

Draw Tube: Blue Top

Sample Type: Citrated Plasma

Specimen Requirements

Sample Type Volume Required Minimum Volume Stability
PREFERRED Citrated Plasma 1mL 0.5mL Frozen (-20C): 2 weeks
Frozen (-80C): 6 months
ALTERNATIVE - - - -
REJECTION CRITERIA Thawed in transit, refrozen or clotted sample
SPECIAL INSTRUCTIONS -

General Information

METHODOLOGY Clot-based
STAT TAT < 24 hours (7 days a week)
STAT TAT Performance > 90% of results released in 24 hours 7 days a week
ROUTINE TAT < 24 hours (M-F)
ALTERNATIVE NAMES Activated Partial Thromboplastin Time, PTT
DESCRIPTION Coagulation screening assay using an aPTT reagent with synthetic phospholipids and colloidal silica activator.
LIMITATIONS -
NORMAL RANGE 25.1-36.5 seconds
ASSOCIATED TESTING -
REFERENCES -
SAMPLE REPORT Upon request
NEW YORK STATE APPROVED -

Test Codes

ORDER CODE P3083
CPT CODE 85730
LOINC CODE 14979-9