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Hypercoagulability Panel

Justification

This panel was designed as an initial work-up to detect the most common causes of thrombophilia in patients suspected of being at risk for thrombosis.

Panel Component Tests

aPTT-LA (Lupus Sensitive) Russell Viper Venom Time (dilute) Anticardiolipin Antibody (IgG, IgM, IgA) Antithrombin III Activity Protein C Activity Protein S Activity Factor V (5) Leiden Gene Mutation Prothrombin (F2) Gene Mutation (G20210A) Factor VIII (8) Activity Homocysteine

STAT: < 48 hours (M-F)

Clot-based, ELISA, RT-PCR

Draw Tube: Purple Top

Draw Tube: Blue Top

Draw Tube: Red Top

Sample Type: Citrated Plasma and Serum and EDTA Whole Blood

Specimen Requirements

Sample Type Volume Required Minimum Volume Stability
PREFERRED Citrated Plasma and Serum and EDTA Whole Blood Five aliquots, 1mL each (Citrated Plasma);Two aliquot, 1mL (Serum); 3mL EDTA tube (Whole Blood) Five aliquots, 0.5mL each (Citrated Plasma);Two aliquot, 0.5mL (Serum); 1mL EDTA tube (Whole Blood) Room Temp.: for Whole Blood
Frozen (-20C): 2 weeks (plasma and serum)
Frozen (-80C): 6 months (plasma and serum)
ALTERNATIVE - - - -
REJECTION CRITERIA Frozen samples thawed in transit, refrozen or clotted sample; whole blood compromised
SPECIAL INSTRUCTIONS -

General Information

METHODOLOGY Clot-based, ELISA, RT-PCR
STAT TAT < 48 hours (M-F)
STAT TAT Performance > 90% of results released in 48 hours
ROUTINE TAT < 1 week
ALTERNATIVE NAMES Hypercoag Panel, Thrombophilia Panel, Thrombosis Panel
DESCRIPTION -
LIMITATIONS -
NORMAL RANGE Interpretation: Normal
ASSOCIATED TESTING -
REFERENCES -
SAMPLE REPORT Upon request
NEW YORK STATE APPROVED Yes

Test Codes

ORDER CODE P1179
CPT CODE 86147x3, 85300, 85730, 81241, 85240, 83090, 85303, 85306, 81240, 85613
LOINC CODE 3181-5, 3182-3, 5076-5, 3174-0, 34571-0, 21667-1, 3209-4, 13965-9, 6007-9, 27822-6, 24476-4, 6303-2