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Factor X (10) Activity

Justification

Congenital deficiency of Factor X is a rare inherited disorder resulting in increased bleeding tendency. Deficiencies in Factor X activity may also be acquired secondary to other diseases such as liver disease, disseminated intravascular coagulation (DIC), vitamin K deficiency, or the development of a specific factor inhibitor.

STAT: < 24 hours (7 days a week)

Clot-based

Draw Tube: Blue Top

Sample Type: Citrated Plasma

Specimen Requirements

Sample Type Volume Required Minimum Volume Stability
PREFERRED Citrated Plasma 1mL 0.5mL Frozen (-20C): 2 weeks
Frozen (-80C): 6 months
ALTERNATIVE - - - -
REJECTION CRITERIA Thawed in transit, refrozen or clotted sample
SPECIAL INSTRUCTIONS -

General Information

METHODOLOGY Clot-based
STAT TAT < 24 hours (7 days a week)
STAT TAT Performance > 90% of results released in 24 hours 7 days a week
ROUTINE TAT < 3 days (M-F)
ALTERNATIVE NAMES Stuart-Prower Factor, F10, FX
DESCRIPTION This is a clot-based assay for the determination of Factor X Activity level in citrated plasma. Patient sample at three different dilutions is mixed with Factor X Deficient plasma containing normal levels of all other factors, such that the resulting Prothrombin Time is dependent only on the level of Factor X present in the patient sample. This value is compared to a reference curve generated from calibrators with known levels of Factor X Activity.
LIMITATIONS -
NORMAL RANGE 68-144%
ASSOCIATED TESTING -
REFERENCES -
SAMPLE REPORT Upon request
NEW YORK STATE APPROVED No

Test Codes

ORDER CODE P3056
CPT CODE 85260
LOINC CODE 3218-5