specialists in coagulation testing









#M3342: ADAMTS-13 Antibody ELISA

COMPONENTS
Name Method Ref Range Units Panic
Value
Frequency
ADAMTS-13 Antibody ELISA ELISA Negative Positive

SPECIMEN REQUIREMENTS
Name Type Volume Aliquot # Temp Container Type Primary/
Alternate
ADAMTS-13 Antibody ELISA Citrated Plasma 1.0mL 1 Frozen or Room Temp Blue Top

GENERAL INFORMATION
Abbreviations vWF-cp Antibody
Test Frequency Weekly
Alternate Names vWF-cleaving Protease Antibody
CPT Code 83520
Notes Thrombotic Thrombocytopenic Purpura (TTP) is characterized by the acquired or congenital deficiency of ADAMTS-13 activity. An antibody inhibitor will be present in roughly half of the cases diagnosed with idiopathic TTP.

Early diagnosis is paramount. Left untreated, TTP has a mortality rate above 90%; however, rapid diagnosis and treatment with plasma exchange improve the mortality rate to below 20%.

ADAMTS-13 Antibody is an important test in the differentiation of acquired and congenital forms of TTP.
 
© 2014 Machaon Diagnostics, Inc.