#M3342: ADAMTS-13 Antibody ELISA COMPONENTS Name Method Ref Range Units Panic Value Frequency ADAMTS-13 Antibody ELISA ELISA Negative Positive Weekly SPECIMEN REQUIREMENTS Name Type Volume Aliquot # Temp Container Type Primary/ Alternate ADAMTS-13 Antibody ELISA Citrated Plasma 1.0mL 1 Frozen or Room Temp Blue Top GENERAL INFORMATION Abbreviations vWF-cp Antibody Test Frequency Weekly Alternate Names vWF-cleaving Protease Antibody CPT Code 83520 Notes Thrombotic Thrombocytopenic Purpura (TTP) is characterized by the acquired or congenital deficiency of ADAMTS-13 activity. An antibody inhibitor will be present in roughly half of the cases diagnosed with idiopathic TTP. Early diagnosis is paramount. Left untreated, TTP has a mortality rate above 90%; however, rapid diagnosis and treatment with plasma exchange improve the mortality rate to below 20%. ADAMTS-13 Antibody is an important test in the differentiation of acquired and congenital forms of TTP.

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