#M3337: ADAMTS-13 Inhibitor ELISA COMPONENTS Name Method Ref Range Units Panic Value Frequency ADAMTS-13 Inhibitor ELISA ELISA Negative Positive Daily SPECIMEN REQUIREMENTS Name Type Volume Aliquot # Temp Container Type Primary/ Alternate ADAMTS-13 Inhibitor ELISA Citrated Plasma 1.0mL 1 Frozen or Room Temp Blue Top GENERAL INFORMATION Abbreviations vWF-cp Inhibitor Test Frequency M, Tue, W, Th, F, Sat, Sun Alternate Names vWF-cleaving Protease Inhibitor CPT Codes 85397, 85335 Notes Thrombotic Thrombocytopenic Purpura (TTP) is characterized by the acquired or congenital deficiency of ADAMTS-13 activity. An antibody inhibitor will be present in roughly half of the cases diagnosed with idiopathic TTP. Early diagnosis is paramount. Left untreated, TTP has a mortality rate above 90%; however, rapid diagnosis and treatment with plasma exchange improve the mortality rate to below 20%. ADAMTS-13 Inhibitor is an important test in the differentiation of acquired and congenital forms of TTP. To maximize the clinical utility of this test, Machaon Diagnostics is offering ADAMTS-13 activity and inhibitor testing on a daily basis with clinical consultation. Weekend testing is available to contracted clients. Please phone the lab for further information.

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