#M3319: Warfarin Sensitivity with Initiation Dose COMPONENTS Name Method Ref Range Units Panic Value Frequency Method Description Warfarin Sensitivity with Initiation Dose Molecular Detection CYP2C9 *1/*1, VKORC1 B/B Daily FDA-approved, array-base analysis SPECIMEN REQUIREMENTS Name Type Volume Aliquot # Temp Container Type Primary/ Alternate Instructions Warfarin Sensitivity with Initiation Dose Whole Blood 5mL 1 Room Temp Lavendar Top No processing required. A current PT/INR result must be submitted with this sample. GENERAL INFORMATION Abbreviations *1, *2, *3, CYP2C9, VKORC1 Test Frequency SAM-DAY Results Alternate Names CYP2C9, VKORC1, Coumadin Sensitivity CPT Codes 83891, 83896*11, 83908*3, 83912, 88385 Notes Together, CYP2C9 and VKORC1 status along with age, weight, CHF and malignancy status, and amiodarone use explain up to 55% of the variation in warfarin maintenance doses.

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